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Effects of fluvoxamine on behavioral and psychological symptoms of dementia in Alzheimer's disease: a report of three cases
https://fmu.repo.nii.ac.jp/records/2001730
https://fmu.repo.nii.ac.jp/records/20017307473bf09-04e8-4173-9827-328112a92636
| 名前 / ファイル | ライセンス | アクション |
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FksmJMedSci_52_p143.pdf (449.1 KB)
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| Item type | デフォルトアイテムタイプ（フル）fmu(1) | |||||||||||||||||||||
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| 公開日 | 2011-05-26 | |||||||||||||||||||||
| タイトル | ||||||||||||||||||||||
| タイトル | Effects of fluvoxamine on behavioral and psychological symptoms of dementia in Alzheimer's disease: a report of three cases | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 作成者 |
Kurita, Masatake
× Kurita, Masatake
× Sato, Tadahiro
× Nishino, Satoshi
× Ohtomo, Koji
× Shirakawa, Hisayoshi
× Mashiko, Hirobumi
× Niwa, Shin-Ichi
× Nakahata, Norimichi
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| 権利情報 | ||||||||||||||||||||||
| 権利情報 | © 2006 The Fukushima Society of Medical Science | |||||||||||||||||||||
| 内容記述 | ||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||
| 内容記述 | OBJECTIVE: To report 3 cases of severe behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease (AD) with fluvoxamine treatment and to discuss the treatment implications for use of the drug. CASE SUMMARY: An 83-year-old woman was diagnosed with AD. Before treatment, she showed sudden irritation and excitement. Her BEHAVE-AD score was 40. She was started on fluvoxamine and quetiapine. Eight weeks later, she was friendly and thankful towards the staff. Her BEHAVE-AD score was 10. The second case was a 79-year-old woman diagnosed with AD. Before treatment, she attempted to leave our hospital and wandered and shouted throughout the day. Her BEHAVE-AD score was 42. She was started on fluvoxamine, and the dosage was gradually increased. Eight weeks later, the shouting and excitement disappeared almost completely. Her BEHAVE-AD score was 13. The third case was a 79-year-old man diagnosed with AD. Before treatment, we put him in a private, locked room because he was extremely agitated and violent because of delusions. His BEHAVE-AD score was 42. He was started on fluvoxamine and sodium valproate. Eight weeks later, the delusion became mild and did not affect his mood or behavior. His BEHAVE-AD score at this point was 4. DISCUSSION: Fluvoxamine was effective in controlling BPSD with AD. This finding shows that the pathophysiology of BPSD due to AD may occur because of a hyposerotonergic state in the brain. CONCLUSION: These cases show that fluvoxamine appears to be effective in the control of BPSD with AD. | |||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||
| 出版者 | The Fukushima Society of Medical Science | |||||||||||||||||||||
| 言語 | ||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||
| 書誌情報 |
en : Fukushima Journal of Medical Science 巻 52, 号 2, p. 143-148, 発行日 2006-12 |
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| 関連タイプ | isIdenticalTo | |||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||
| 関連識別子 | https://doi.org/10.5387/fms.52.143 | |||||||||||||||||||||
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| 識別子タイプ | PMID | |||||||||||||||||||||
| 関連識別子 | 17427765 | |||||||||||||||||||||
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| 識別子タイプ | ICHUSHI | |||||||||||||||||||||
| 関連識別子 | 2007203256 | |||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||
| 収録物識別子 | ||||||||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||||||||
| 収録物識別子 | 0016-2590 | |||||||||||||||||||||
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| 収録物識別子タイプ | EISSN | |||||||||||||||||||||
| 収録物識別子 | 2185-4610 | |||||||||||||||||||||
| 収録物識別子 | ||||||||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||||||||
| 収録物識別子 | AA0065246X | |||||||||||||||||||||
| 主題 | ||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||
| 主題 | Alzheimer's disease, AD | |||||||||||||||||||||
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| 主題Scheme | Other | |||||||||||||||||||||
| 主題 | behavioral and psychological symptoms of dementia, BPSD | |||||||||||||||||||||
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| 主題Scheme | Other | |||||||||||||||||||||
| 主題 | Behavioral Pathology in Alzheimer's Disease Rating Scale, BEHAVE-AD | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Aged | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Aged, 80 and over | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Alzheimer Disease | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Behavioral Symptoms | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Female | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Fluvoxamine | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Humans | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Male | |||||||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||||||
| 主題 | Serotonin Uptake Inhibitors | |||||||||||||||||||||
