{"created":"2024-11-29T05:20:56.930199+00:00","id":2001730,"links":{},"metadata":{"_buckets":{"deposit":"472e73d4-c2b1-4699-86b6-f8a8f43b41fa"},"_deposit":{"created_by":8,"id":"2001730","owners":[8],"pid":{"revision_id":0,"type":"depid","value":"2001730"},"status":"published"},"_oai":{"id":"oai:fmu.repo.nii.ac.jp:02001730","sets":["1732778801467:1732778962699:1732856458937"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Effects of fluvoxamine on behavioral and psychological symptoms of dementia in Alzheimer's disease: a report of three cases","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kurita, Masatake","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sato, Tadahiro","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nishino, Satoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ohtomo, Koji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shirakawa, Hisayoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Mashiko, Hirobumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Niwa, Shin-Ichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakahata, Norimichi","creatorNameLang":"en"}]}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2006 The Fukushima Society of Medical Science","subitem_rights_language":"en"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Alzheimer's disease, AD","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"behavioral and psychological symptoms of dementia, BPSD","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Behavioral Pathology in Alzheimer's Disease Rating Scale, BEHAVE-AD","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Aged","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"},{"subitem_subject":"Aged, 80 and over","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"},{"subitem_subject":"Alzheimer Disease","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"},{"subitem_subject":"Behavioral Symptoms","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"},{"subitem_subject":"Female","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"},{"subitem_subject":"Fluvoxamine","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"},{"subitem_subject":"Humans","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"},{"subitem_subject":"Male","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"},{"subitem_subject":"Serotonin Uptake Inhibitors","subitem_subject_language":"en","subitem_subject_scheme":"MeSH"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"OBJECTIVE: To report 3 cases of severe behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease (AD) with fluvoxamine treatment and to discuss the treatment implications for use of the drug. CASE SUMMARY: An 83-year-old woman was diagnosed with AD. Before treatment, she showed sudden irritation and excitement. Her BEHAVE-AD score was 40. She was started on fluvoxamine and quetiapine. Eight weeks later, she was friendly and thankful towards the staff. Her BEHAVE-AD score was 10. The second case was a 79-year-old woman diagnosed with AD. Before treatment, she attempted to leave our hospital and wandered and shouted throughout the day. Her BEHAVE-AD score was 42. She was started on fluvoxamine, and the dosage was gradually increased. Eight weeks later, the shouting and excitement disappeared almost completely. Her BEHAVE-AD score was 13. The third case was a 79-year-old man diagnosed with AD. Before treatment, we put him in a private, locked room because he was extremely agitated and violent because of delusions. His BEHAVE-AD score was 42. He was started on fluvoxamine and sodium valproate. Eight weeks later, the delusion became mild and did not affect his mood or behavior. His BEHAVE-AD score at this point was 4. DISCUSSION: Fluvoxamine was effective in controlling BPSD with AD. This finding shows that the pathophysiology of BPSD due to AD may occur because of a hyposerotonergic state in the brain. CONCLUSION: These cases show that fluvoxamine appears to be effective in the control of BPSD with AD.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"The Fukushima Society of Medical Science","subitem_publisher_language":"en"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0016-2590","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2185-4610","subitem_source_identifier_type":"EISSN"},{"subitem_source_identifier":"AA0065246X","subitem_source_identifier_type":"NCID"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"148","bibliographicPageStart":"143","bibliographicVolumeNumber":"52","bibliographic_titles":[{"bibliographic_title":"Fukushima Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.5387/fms.52.143","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"17427765","subitem_relation_type_select":"PMID"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"2007203256","subitem_relation_type_select":"ICHUSHI"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2011-05-26"}],"displaytype":"detail","filename":"FksmJMedSci_52_p143.pdf","filesize":[{"value":"449.1 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://fmu.repo.nii.ac.jp/record/2001730/files/FksmJMedSci_52_p143.pdf"},"version_id":"21af6ca1-ecab-4c72-a184-eb036490dee6"}]},"item_title":"Effects of fluvoxamine on behavioral and psychological symptoms of dementia in Alzheimer's disease: a report of three cases","item_type_id":"40002","owner":"8","path":["1732856458937"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-05-26"},"publish_date":"2011-05-26","publish_status":"0","recid":"2001730","relation_version_is_last":true,"title":["Effects of fluvoxamine on behavioral and psychological symptoms of dementia in Alzheimer's disease: a report of three cases"],"weko_creator_id":"8","weko_shared_id":-1},"updated":"2024-11-29T05:33:53.092601+00:00"}