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Clinical features of liver dysfunction in collagen diseases
https://fmu.repo.nii.ac.jp/records/2000022
https://fmu.repo.nii.ac.jp/records/20000220c92a3b6-2fdc-45f6-a5d4-951706ce0e84
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HepatolRes_40_p1092.pdf (378.9 KB)
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| Item type | デフォルトアイテムタイプ（フル）fmu(1) | |||||||||||||||||||||
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| 公開日 | 2013-08-02 | |||||||||||||||||||||
| タイトル | ||||||||||||||||||||||
| タイトル | Clinical features of liver dysfunction in collagen diseases | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 作成者 |
Takahashi, Atsushi
× Takahashi, Atsushi
× Abe, Kazumichi
× Yokokawa, Junko
× Iwadate, Haruyo
× Kobayashi, Hiroko
× Watanabe, Hiroshi
× Irisawa, Atsushi
× Ohira, Hiromasa
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| 権利情報 | ||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 権利情報 | Author posting. © The Japan Society of Hepatology 2010. This is the author’s version of the work. It is posted here by permission of Hepatology Research. 40(11):1092-1097. http://dx.doi.org/10.1111/j.1872-034X.2010.00707.x | |||||||||||||||||||||
| 主題 | ||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||
| 主題 | collagen disease | |||||||||||||||||||||
| 主題 | ||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||
| 主題 | liver dysfunction | |||||||||||||||||||||
| 内容記述 | ||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||
| 内容記述 | Aim: Liver dysfunction is not rare in patients with collagen disease. We sought to elucidate the clinical features of liver dysfunction in the presence of collagen disease. Methods: We analyzed the frequency and causes of liver dysfunction in 607 patients (rheumatoid arthritis [RA], n = 220; systemic lupus erythematosus [SLE], n = 164; systemic sclerosis [SSc], n = 47; Sjögren's syndrome [SjS], n = 44; Behçet's disease, n = 43; polymyositis/dermatomyositis [PM/DM], n = 27; vasculitis syndrome, n = 25; mixed connective tissue disease [MCTD], n = 21; and adult-onset Still's disease [AOSD], n = 16). Results: Liver dysfunction was observed in 238 (39.2%) of 607 patients showing collagen disease. Patients with AOSD (81.3%), PM/DM (51.9%) and vasculitis syndrome (48.0%) frequently displayed liver dysfunction. Liver dysfunction in collagen diseases results from many causes; drug-induced liver injury (26.1%), fatty liver (7.6%), viral hepatitis (1.3%), autoimmune hepatitis (4.2%), primary biliary cirrhosis (15.9%) and the collagen disease itself (15.5%). Conversely, primary biliary cirrhosis was a leading cause in SSc (76.1%) and SjS (70.0%). Liver dysfunction in collagen disease tended to be mild. In addition, alanine aminotransferase levels correlated positively with ferritin levels in AOSD (R = 0.708, P < 0.05). Moreover, alkaline phosphatase levels correlated positively with C reactive protein levels in vasculitis syndrome (R = 0.833, P < 0.05). Conclusion: Liver dysfunction in the presence of collagen disease has various causes, and dysfunction associated with collagen disease reflects the activity of the collagen disease itself. | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||
| 出版者 | Wiley-Blackwell | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 言語 | ||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||
| 出版タイプ | AM | |||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||||||||
| 関連情報 | ||||||||||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||
| 関連識別子 | https://doi.org/10.1111/j.1872-034X.2010.00707.x | |||||||||||||||||||||
| 関連情報 | ||||||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||||||
| 関連識別子 | 20880057 | |||||||||||||||||||||
| 収録物識別子 | ||||||||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||||||||
| 収録物識別子 | 1386-6346 | |||||||||||||||||||||
| 収録物識別子 | ||||||||||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||||||||||
| 収録物識別子 | 1872-034X | |||||||||||||||||||||
| 収録物識別子 | ||||||||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||||||||
| 収録物識別子 | AA11140867 | |||||||||||||||||||||
| 書誌情報 |
en : Hepatology Research 巻 40, 号 11, p. 1092-1097, 発行日 2010-11 |
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