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  1. 福島医学会
  2. Fukushima Journal of Medical Science
  3. Vol.71 (2025)

Recent topics in diagnosis and treatment of malignant spinal tumors

https://fmu.repo.nii.ac.jp/records/2002371
https://fmu.repo.nii.ac.jp/records/2002371
f97b7549-4577-461c-9a0b-75803bf91dd8
名前 / ファイル ライセンス アクション
FksmJMedSci_71_p85.pdf FksmJMedSci_71_p85.pdf
Item type デフォルトアイテムタイプ(フル)fmu(1)
公開日 2025-04-23
タイトル
タイトル Recent topics in diagnosis and treatment of malignant spinal tumors
言語 en
作成者 Matsumoto, Yoshihiro

× Matsumoto, Yoshihiro

en Matsumoto, Yoshihiro

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権利情報
権利情報Resource https://creativecommons.org/licenses/by-nc-sa/4.0/
権利情報 © 2025 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
内容記述
内容記述タイプ Abstract
内容記述 The diagnosis and treatment of malignant spinal tumors are complex and require an integrated approach known as Jaffe’s triangle. This review discusses recent topics in the diagnosis and treatment of primary and metastatic malignant spinal tumors. Integrated diagnostic methods, including the development of a dumbbell scoring system for benign-malignant differentiation and the use of positron emission tomography and magnetic resonance imaging (PET-MRI), have improved diagnostic accuracy. Curative resection techniques such as vertebrectomy, sagittal resection, and posterior resection are crucial for primary malignant tumors. Heavy particle radiation therapy, such as carbon-ion radiotherapy, shows promise against radiation-resistant tumors, whereas novel drug therapies, such as denosumab, are effective for giant cell tumors of the bone arising in the spine. For metastatic spinal tumors, the collaborative efforts of the Bone Metastasis Cancer Board and minimally invasive spine stabilization have expanded surgical indications and improved patient outcomes. The treatment system has shifted towards preventive surgery and outpatient management, aiming to maintain quality of life and continue chemotherapy. Interdisciplinary collaboration is essential for improving treatment outcomes in both primary and metastatic malignant spinal tumors. Primary malignant spinal cord tumors (PMST) and metastatic spinal tumors (MST) are among the most difficult areas of orthopedic surgery. Their diagnosis and treatment require multidisciplinary diagnostic and therapeutic strategies that integrate knowledge and skills in orthopedics, pathology, and diagnostic radiology (the so-called Jaffe triangle), as well as in clinical oncology and tumor biology, which have made remarkable progress in recent years. Here, we review recent topics related to the diagnosis and treatment of PMST and MST.
出版者
出版者 The Fukushima Society of Medical Science
言語
言語 eng
書誌情報 en : Fukushima journal of medical science

巻 72, 号 2, p. 85-95, 発行日 2025
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.5387/fms.24-00008
関連情報
識別子タイプ PMID
関連識別子 39909449
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0016-2590
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2185-4610
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA0065246X
主題
主題Scheme Other
主題 Primary malignant spinal tumors
主題
主題Scheme Other
主題 Metastatic spinal tumors
主題
主題Scheme Other
主題 diagnosis and treatment
主題
主題Scheme MeSH
主題 Humans
主題
主題Scheme MeSH
主題 Spinal Neoplasms
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