Item type |
デフォルトアイテムタイプ(フル)fmu(1) |
公開日 |
2025-03-28 |
タイトル |
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タイトル |
External Radiation Dose, Obesity, and Risk of Childhood Thyroid Cancer After the Fukushima Daiichi Nuclear Power Plant Accident: The Fukushima Health Management Survey |
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言語 |
en |
作成者 |
Ohira, Tetsuya
Ohtsuru, Akira
Midorikawa, Sanae
Takahashi, Hideto
Yasumura, Seiji
Suzuki, Satoru
Matsuzuka, Takashi
Shimura, Hiroki
Ishikawa, Tetsuo
Sakai, Akira
Suzuki, Shinichi
Yamashita, Shunichi
Yokoya, Susumu
Tanigawa, Koichi
Ohto, Hitoshi
Kamiya, Kenji
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権利情報 |
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権利情報 |
Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved. This is a non-final version of an article published in final form in Epidemiology. 2019 Nov;30(6):853-860. |
内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
BACKGROUND: The 2011 Great East Japan Earthquake led to a nuclear accident at Fukushima Daiichi Nuclear Power Plant. This study examines the associations of radiation dose and lifestyle factors with incidence of thyroid cancer in Fukushima. METHODS: We designed a prospective study with 300,473 participants aged 18 years or younger, who underwent thyroid examinations from October 2011. Follow-up surveys were conducted through June 2017, and 245,530 participants (123,480 men and 122,050 women, 82% follow-up) received follow-up examinations. Fukushima Prefecture was divided into five areas based on individual external radiation dose. We calculated relative risks and 95% confidence intervals (CIs) for thyroid cancer in each area, with area of lowest dose as reference, using age-adjusted Poisson regression models. We also calculated risks associated with overweight and obesity. RESULTS: The incidence per 100,000 for Groups A (highest dose), B, C, D, and E (lowest dose) were 13.5, 19.2, 17.3, 9.0, and 8.3, respectively. Compared with Group E, the age-adjusted risks (95% CIs) were 1.62 (0.59, 4.47) for group A, 2.32 (0.86, 6.24) for group B, 2.21 (0.82, 5.94) for group C, and 1.02 (0.36, 2.86) for group D. Obesity was positively associated with thyroid cancer incidence; the multivariable-adjusted risk of thyroid cancer was 2.23 (1.01, 4.90) for obese individuals compared with nonobese individuals. CONCLUSION: Regional differences in radiation dose were not associated with increased risk of thyroid cancer among children in Fukushima within 4 to 6 years after the nuclear power plant accident. Obesity may be an important factor for further follow-up in Fukushima. |
出版者 |
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出版者 |
Wolters Kluwer Health |
言語 |
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言語 |
eng |
書誌情報 |
en : Epidemiology
巻 30,
号 6,
p. 853-860,
発行日 2019-11
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関連情報 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1097/ede.0000000000001058 |
関連情報 |
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識別子タイプ |
PMID |
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関連識別子 |
31259849 |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版タイプ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1044-3983 |
収録物識別子 |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
1531-5487 |
収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA10832184 |
主題 |
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主題Scheme |
Other |
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主題 |
Childhood |
主題 |
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主題Scheme |
Other |
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主題 |
Disaster |
主題 |
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主題Scheme |
Other |
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主題 |
Epidemiology |
主題 |
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主題Scheme |
Other |
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主題 |
Population-based |
主題 |
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主題Scheme |
Other |
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主題 |
Prospective study |
主題 |
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主題Scheme |
Other |
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主題 |
Radiation |
主題 |
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主題Scheme |
Other |
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主題 |
Thyroid gland |
主題 |
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主題Scheme |
MeSH |
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主題 |
Adolescent |
主題 |
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主題Scheme |
MeSH |
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主題 |
Carcinoma |
主題 |
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主題Scheme |
MeSH |
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主題 |
Child |
主題 |
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主題Scheme |
MeSH |
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主題 |
Child, Preschool |
主題 |
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主題Scheme |
MeSH |
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主題 |
Female |
主題 |
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主題Scheme |
MeSH |
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主題 |
Fukushima Nuclear Accident |
主題 |
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主題Scheme |
MeSH |
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主題 |
Humans |
主題 |
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主題Scheme |
MeSH |
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主題 |
Incidence |
主題 |
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主題Scheme |
MeSH |
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主題 |
Infant |
主題 |
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主題Scheme |
MeSH |
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主題 |
Infant, Newborn |
主題 |
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主題Scheme |
MeSH |
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主題 |
Japan |
主題 |
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主題Scheme |
MeSH |
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主題 |
Male |
主題 |
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主題Scheme |
MeSH |
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主題 |
Multivariate Analysis |
主題 |
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主題Scheme |
MeSH |
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主題 |
Obesity |
主題 |
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主題Scheme |
MeSH |
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主題 |
Radiation Dosage |
主題 |
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主題Scheme |
MeSH |
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主題 |
Thyroid Neoplasms |
主題 |
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主題Scheme |
MeSH |
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主題 |
Ultrasonography |