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  1. 福島医学会
  2. Fukushima Journal of Medical Science
  3. Vol.68 (2022)

Association between the presence of bacteria in prostate tissue and histopathology in biopsies from men not complaining of lower urinary tract symptoms

https://fmu.repo.nii.ac.jp/records/2002057
https://fmu.repo.nii.ac.jp/records/2002057
3a1a9a8e-203b-4894-8ff8-189f27b1c12e
名前 / ファイル ライセンス アクション
FksmJMedSci_68_p161.pdf FksmJMedSci_68_p161.pdf (451.0 KB)
Item type デフォルトアイテムタイプ(フル)fmu(1)
公開日 2022-12-23
タイトル
タイトル Association between the presence of bacteria in prostate tissue and histopathology in biopsies from men not complaining of lower urinary tract symptoms
言語 en
作成者 Honda-Takinami, Ruriko

× Honda-Takinami, Ruriko

en Honda-Takinami, Ruriko

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Hata, Junya

× Hata, Junya

en Hata, Junya

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Matsuoka, Kanako

× Matsuoka, Kanako

en Matsuoka, Kanako

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Hoshi, Seiji

× Hoshi, Seiji

en Hoshi, Seiji

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Koguchi, Tomoyuki

× Koguchi, Tomoyuki

en Koguchi, Tomoyuki

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Sato, Yuichi

× Sato, Yuichi

en Sato, Yuichi

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Akaihata, Hidenori

× Akaihata, Hidenori

en Akaihata, Hidenori

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Kataoka, Masao

× Kataoka, Masao

en Kataoka, Masao

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Ogawa, Soichiro

× Ogawa, Soichiro

en Ogawa, Soichiro

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Nishiyama, Kyoko

× Nishiyama, Kyoko

en Nishiyama, Kyoko

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Suzutani, Tatsuo

× Suzutani, Tatsuo

en Suzutani, Tatsuo

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Kojima, Yoshiyuki

× Kojima, Yoshiyuki

en Kojima, Yoshiyuki

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権利情報
権利情報Resource https://creativecommons.org/licenses/by-nc-sa/4.0/
権利情報 © 2022 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
内容記述
内容記述タイプ Abstract
内容記述 Objective: To investigate the presence of bacteria in prostate tissue, and relationships between the bacteria and histopathological findings. Methods: Samples were collected from prostate biopsy patients with no obvious lower urinary tract symptoms (LUTS). Detection and identification of bacterial species in the prostate tissues were performed with PCR for 16SrDNA and DNA sequencing. Histopathology was also evaluated. LUTS and lower urinary tract function were assessed by questionnaires, uroflowmetry, and ultrasonography. Results: DNA was extracted from 97 prostate biopsies, with 5 bacterial species detected among samples from 7 patients (7.2%). The stroma-to-gland ratio in the prostate tissues from patients with bacteria was lower than in those without bacteria (p < 0.01). Glandular epithelial hyperplasia was also identified in the prostates harboring bacteria. International Prostate Symptom Score (IPSS), IPSS-quality of life (IPSS-QOL), Overactive Bladder Symptom Score (OABSS), maximum flow rate, urine volume by uroflowmetry, and post-voided residual urine were not significantly different when comparing patients with and without bacteria in their prostate samples. Conclusions: The present study demonstrated that 7.2% of men without obvious LUTS had bacteria in their prostate tissues. The presence of such bacteria might induce glandular hyperplasia and contribute to pathological changes in the early stages of benign prostate enlargement before affecting LUTS.
出版者
出版者 The Fukushima Society of Medical Science
言語
言語 eng
書誌情報 en : Fukushima Journal of Medical Science

巻 68, 号 3, p. 161-167, 発行日 2022
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.5387/fms.2022-34
関連情報
識別子タイプ PMID
関連識別子 36372441
関連情報
識別子タイプ ICHUSHI
関連識別子 2024061740
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0016-2590
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2185-4610
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA0065246X
主題
主題Scheme Other
主題 bacteria
主題
主題Scheme Other
主題 lower urinary tract symptoms
主題
主題Scheme Other
主題 prostate
主題
主題Scheme Other
主題 glandular hyperplasia
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