| Item type |
デフォルトアイテムタイプ（フル）fmu(1) |
| 公開日 |
2022-04-15 |
| タイトル |
|
|
タイトル |
Successful pregnancy and delivery after a vitrified-warmed embryo transfer in a woman with Kallmann syndrome: A case report and literature review |
|
言語 |
en |
| 作成者 |
Shiraiwa, Aya
Takahashi, Toshifumi
Okoshi, Chihiro
Wada, Marina
Ota, Kuniaki
Suganuma, Ryota
Jimbo, Masatoshi
Soeda, Shu
Watanabe, Takafumi
Yoshida-Komiya, Hiromi
Fujimori, Keiya
|
| 権利情報 |
|
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
|
権利情報 |
© 2022 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
Kallmann syndrome, a congenital disorder of idiopathic hypogonadotropic hypogonadism associated with anosmia, results in infertility because of anovulation. Assisted reproductive technology (ART) is considered when optimal ovulation induction therapy is difficult or when several cycles of ovulation induction therapy do not result in pregnancy. However, evidence is lacking regarding the optimal ART treatment for Kallmann syndrome. We report the case of a 33-year-old woman who successfully achieved pregnancy and delivery after ART treatment. At 29 years old, she was diagnosed with Kallmann syndrome due to hypothalamic amenorrhea and anosmia. At 33 years old, she revisited the hospital, desiring a child after one year of infertility. Due to anovulation, she was treated with gonadotropin therapy, but controlling follicular development was difficult, and thus ART treatment was initiated. The controlled ovarian stimulation (COS) protocol for ART treatment employed gonadotropins, recombinant follicular stimulating hormone/human menopausal gonadotropin plus human chorionic gonadotropin, to promote follicular growth. Four oocytes were retrieved, and two cleaved embryos were vitrified and cryopreserved. After vitrified-warmed embryo transfer of a morula stage embryo in a hormone replacement cycle, pregnancy was achieved but resulted in a miscarriage. A second oocyte retrieval was performed under the same COS; four oocytes were retrieved, and two cleaved embryos were vitrified and cryopreserved. Further, a pregnancy was achieved through the vitrified warmed embryo transfer. At 40 weeks and 6 days of gestation, a baby boy weighing 3,344 g with an Apgar score of 7/8 was delivered vaginally. The mother's postpartum course and neonate were free from adverse events. For women with Kallmann syndrome, ART treatment and selective embryo cryopreservation may be a reasonable and safe option. |
| 出版者 |
|
|
出版者 |
The Fukushima Society of Medical Science |
| 言語 |
|
|
言語 |
eng |
| 書誌情報 |
en : Fukushima Journal of Medical Science
巻 68,
号 1,
p. 49-55,
発行日 2022
|
| 関連情報 |
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関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.5387/fms.2021-09 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
35314524 |
| 関連情報 |
|
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|
識別子タイプ |
ICHUSHI |
|
|
関連識別子 |
2023116783 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0016-2590 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2185-4610 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0065246X |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Kallmann syndrome |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
gonadotropin therapy |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
assisted reproductive technology |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
frozen-thawed embryo transfer |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Anosmia |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Anovulation |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Embryo Transfer |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Female |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Hormones |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Humans |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Infertility |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Kallmann Syndrome |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Pregnancy |
FksmJMedSci_68_p49.pdf (298.9 KB)
