| Item type |
デフォルトアイテムタイプ（フル）fmu(1) |
| 公開日 |
2021-04-19 |
| タイトル |
|
|
タイトル |
Orthogonal antibody testing for COVID-19 among healthcare workers in a non-epidemic place and time: Japan's Iwate Prefecture, May 18-31, 2020 |
|
言語 |
en |
| 作成者 |
Nakamura, Akihiro
Sato, Ryoichi
Ando, Sanae
Oana, Natsuko
Nozaki, Eiji
Endo, Hideaki
Miyate, Yoshiharu
Soma, Jun
Miyata, Go
|
| 権利情報 |
|
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
|
権利情報 |
© 2021 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Of the 47 prefectures in Japan, Iwate had the fewest cases of coronavirus disease 2019 (COVID-19), with the first diagnosis officially confirmed on July 28, 2020. A baseline serological survey of COVID-19 antibodies is essential to accurately evaluate an epidemic outbreak. The primary purpose of this study was to determine pre-epidemic prevalence of COVID-19 antibodies among healthcare workers, using two laboratory-based quantitative tests. In addition, a point-of-care (POC) qualitative test, rapid, simple, and convenient for primary care clinics, was compared with the laboratory-based tests. All antibody tests were performed on serum from 1,000 healthcare workers (mean age, 40 ± 11 years) in Iwate Prefectural Central Hospital, May 29-31, 2020. A COVID-19 case was defined as showing positive results in both laboratory-based quantitative tests. None of 1,000 samples had positive results in both of the laboratory immunoassays. The POC test showed positive results in 33 of 1,000 samples (3.3%) (95% confidence interval:2.19-4.41), but no samples were simultaneously positive in both laboratory-based tests. In conclusion, COVID-19 cases were not serologically confirmed by a baseline control study of healthcare workers at our hospital in late May, 2020. Moreover, the POC qualitative test may offer no advantage in areas with very low prevalence of COVID-19, due to higher false-positive reactions compared with laboratory-based quantitative immunoassays. |
| 出版者 |
|
|
出版者 |
The Fukushima Society of Medical Science |
| 言語 |
|
|
言語 |
eng |
| 書誌情報 |
en : Fukushima Journal of Medical Science
巻 67,
号 1,
p. 27-32,
発行日 2021
|
| 関連情報 |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.5387/fms.2020-21 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
33642419 |
| 関連情報 |
|
|
|
識別子タイプ |
ICHUSHI |
|
|
関連識別子 |
2021327589 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0016-2590 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2185-4610 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0065246X |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
antibody test |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
COVID-19 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Iwate |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
SARS-CoV-2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
seroprevalence |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Adult |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Antibodies, Viral |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
COVID-19 |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
COVID-19 Serological Testing |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Epidemics |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
False Positive Reactions |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Female |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Health Personnel |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Humans |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Japan |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Male |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Middle Aged |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Pandemics |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Point-of-Care Testing |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
SARS-CoV-2 |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Seroepidemiologic Studies |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Tertiary Care Centers |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Time Factors |
FksmJMedSci_67_p27.pdf (449.1 KB)
