| Item type |
デフォルトアイテムタイプ（フル）fmu(1) |
| 公開日 |
2020-12-11 |
| タイトル |
|
|
タイトル |
Early intra-abdominal infection following pancreaticoduodenectomy:associated factors and clinical impact on surgical outcome |
|
言語 |
en |
| 作成者 |
Sato, Naoya
Kimura, Takashi
Kenjo, Akira
Kofunato, Yasuhide
Okada, Ryo
Ishigame, Teruhide
Watanabe, Junichiro
Marubashi, Shigeru
|
| 権利情報 |
|
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
|
権利情報 |
© 2020 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Early intra-abdominal infection (IAI) following pancreaticoduodenectomy (PD) is an initial event relating to morbidities caused by postoperative pancreatic fistula (POPF). The aims of this study were to determine factors associated with IAI, and to investigate its impact on postoperative outcome.Consecutive patients, 113 in total, who underwent PD at Fukushima Medical University Hospital between January 2012 and September 2017 were included in this retrospective study. IAI was defined by positive bacterial culture from intra-abdominal drainage fluid any time through postoperative day 3 (POD3). Logistic regression analysis was used to identify the relevant factors associated with IAI. The clinical impact of the POD3 infection indicators related to POPF were assessed by multivariate analysis.The incidence of IAI, POPF, and mortality were 36.1%, 36.1%, and 0%, respectively. Independent factors associated with IAI were preoperative biliary drainage (PBD) (OR = 2.91, CI = 1.16-7.33, p = 0.023) and soft pancreas (OR = 8.67, CI = 2.37-31.77, p = 0.001). Among infection markers on POD3, the significant factors for POPF were CRP (OR = 1.18, CI = 1.08-1.30, p < 0.001), IAI (OR = 7,37, CI = 2.53-21.5, p < 0.001), and drain amylase (OR = 1.00, CI = 1.00-1.01, p = 0.001).In conclusion, PBD, soft pancreas, and higher age were associated with IAI. IAI has a significantly negative impact on postoperative outcome. |
| 出版者 |
|
|
出版者 |
The Fukushima Society of Medical Science |
| 言語 |
|
|
言語 |
eng |
| 書誌情報 |
en : Fukushima Journal of Medical Science
巻 66,
号 3,
p. 124-132,
発行日 2020
|
| 関連情報 |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.5387/fms.2020-11 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
32963204 |
| 関連情報 |
|
|
|
識別子タイプ |
ICHUSHI |
|
|
関連識別子 |
2021233988 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0016-2590 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2185-4610 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0065246X |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
pancreaticoduodenectomy |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
postoperative pancreatic fistula |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
surgical site infection |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
early intra-abdominal infection |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
preoperative biliary drainage |
FksmJMedSci_66_p124.pdf (256.7 KB)
