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  1. 福島医学会
  2. Fukushima Journal of Medical Science
  3. Vol.61 (2015)

Outcome of clival chordomas after skull base surgeries with mean follow-up of 10 years

https://fmu.repo.nii.ac.jp/records/2001904
https://fmu.repo.nii.ac.jp/records/2001904
f52abc08-b2d7-407b-b57a-fba77588b55c
名前 / ファイル ライセンス アクション
FksmJMedSci_61_p131.pdf FksmJMedSci_61_p131.pdf (1000.0 KB)
Item type デフォルトアイテムタイプ(フル)fmu(1)
公開日 2015-12-25
タイトル
タイトル Outcome of clival chordomas after skull base surgeries with mean follow-up of 10 years
言語 en
作成者 Tamura, Takamitsu

× Tamura, Takamitsu

en Tamura, Takamitsu

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Sato, Taku

× Sato, Taku

en Sato, Taku

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Kishida, Yugo

× Kishida, Yugo

en Kishida, Yugo

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Ichikawa, Masahiro

× Ichikawa, Masahiro

en Ichikawa, Masahiro

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Oda, Keiko

× Oda, Keiko

en Oda, Keiko

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Ito, Eiji

× Ito, Eiji

en Ito, Eiji

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Watanabe, Tadashi

× Watanabe, Tadashi

en Watanabe, Tadashi

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Sakuma, Jun

× Sakuma, Jun

en Sakuma, Jun

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Saito, Kiyoshi

× Saito, Kiyoshi

en Saito, Kiyoshi

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権利情報
権利情報 © 2015 The Fukushima Society of Medical Science
内容記述
内容記述タイプ Abstract
内容記述 Background and Objective: Skull base chordomas are clinically malignant because of the difficulty of total removal, high recurrence rate, and occasional drop metastasis. Although aggressive surgical resection and postoperative radiation have been recommended, the long-term outcome remains unsatisfactory. Methods: From 1992 to 2011, we treated 24 patients with skull base chordoma using aggressive surgical removal as a principal strategy. Skull base approaches were selected according to tumor extension to remove the tumor and surrounding bone as completely as possible. After surgery, all patients were closely observed with MRI to find small and localized recurrent tumors, which were treated with gamma-knife radiosurgery or surgical resection. The mean postoperative follow-up duration was 10.2 years (range, 1-17.2 years). Results: The 5-, 10-, and 15-year overall survival rates were 86%, 72%, and 72%, respectively. The 5- and 10-year progression-free survival rates were 47% and 35%, respectively. Tumor extension to the brainstem and partial tumor removal were the factors related to poor survival. Conclusions: Our results suggest that aggressive surgical removal improves the long-term outcome of patients with skull base chordoma. We would like to emphasize that skull base chordomas should be aggressively removed using various skull base approaches.
出版者
出版者 The Fukushima Society of Medical Science
言語
言語 eng
書誌情報 en : Fukushima Journal of Medical Science

巻 61, 号 2, p. 131-140, 発行日 2015
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.5387/fms.2015-12
関連情報
識別子タイプ PMID
関連識別子 26370681
関連情報
識別子タイプ ICHUSHI
関連識別子 2017088016
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0016-2590
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2185-4610
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA0065246X
主題
主題Scheme Other
主題 clival chordoma
主題
主題Scheme Other
主題 skull base surgery
主題
主題Scheme Other
主題 long-term outcome
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