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Anti-tumor immune responses induced by radiotherapy: a review
https://fmu.repo.nii.ac.jp/records/2001889
https://fmu.repo.nii.ac.jp/records/200188984ec6a75-5649-4404-80bd-8f135cea43c0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
FksmJMedSci_61_p13.pdf (903.5 KB)
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| Item type | デフォルトアイテムタイプ（フル）fmu(1) | |||||||||||
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| 公開日 | 2015-08-05 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Anti-tumor immune responses induced by radiotherapy: a review | |||||||||||
| 言語 | en | |||||||||||
| 作成者 |
Yoshimoto, Yuya
× Yoshimoto, Yuya
× Kono, Koji
× Suzuki, Yoshiyuki
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| 権利情報 | ||||||||||||
| 権利情報 | © 2015 The Fukushima Society of Medical Science | |||||||||||
| 内容記述 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | An anti-tumor immune response is one of the most important factors that can determine treatment response and prognosis of cancer patients. Recent studies have demonstrated that radiotherapy can activate tumor-specific immune responses and that these responses contribute to the therapeutic efficacy. However, the exact mechanisms underlying the radiation-induced immune responses remain unclear. Better understanding of the mechanisms could facilitate the application of immune-activating radiotherapy and provide new treatment strategies. We previously demonstrated that tumor-specific T cell responses could be induced in esophageal cancer patients during and after chemoradiotherapy. Furthermore, in a mouse model, immune responses played an important role in determining the local and systemic therapeutic efficacy of radiotherapy that could be augmented by the immune checkpoint blockade. In this review, radiotherapy-induced immune responses, the mechanisms underlying the induction of those responses, and a practical application of the therapy are discussed. | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | The Fukushima Society of Medical Science | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 書誌情報 |
en : Fukushima Journal of Medical Science 巻 61, 号 1, p. 13-22, 発行日 2015 |
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| 関連情報 | ||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | https://doi.org/10.5387/fms.2015-6 | |||||||||||
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| 識別子タイプ | PMID | |||||||||||
| 関連識別子 | 26135666 | |||||||||||
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| 識別子タイプ | ICHUSHI | |||||||||||
| 関連識別子 | 2016216415 | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 0016-2590 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||
| 収録物識別子 | 2185-4610 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA0065246X | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | radiotherapy | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | anti-tumor immunity | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | immunotherapy | |||||||||||
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| 主題Scheme | Other | |||||||||||
| 主題 | abscopal effect | |||||||||||
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| 主題Scheme | Other | |||||||||||
| 主題 | cytotoxic T-lymphocyte | |||||||||||
