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  1. 福島医学会
  2. Fukushima Journal of Medical Science
  3. Vol.60 (2014)

Correlations among heavy metals in blood and urine and their relations to depressive symptoms in Parkinson's disease patients

https://fmu.repo.nii.ac.jp/records/2001866
https://fmu.repo.nii.ac.jp/records/2001866
1aae5b57-433d-4f84-a46d-561ba51bdf01
名前 / ファイル ライセンス アクション
FksmJMedSci_60_p108.pdf FksmJMedSci_60_p108.pdf (332.2 KB)
Item type デフォルトアイテムタイプ(フル)fmu(1)
公開日 2015-07-06
タイトル
タイトル Correlations among heavy metals in blood and urine and their relations to depressive symptoms in Parkinson's disease patients
言語 en
作成者 Fukushima, Tetsuhito

× Fukushima, Tetsuhito

en Fukushima, Tetsuhito

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Tan, Xiaodong

× Tan, Xiaodong

en Tan, Xiaodong

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Luo, Yunwen

× Luo, Yunwen

en Luo, Yunwen

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Wang, Puqing

× Wang, Puqing

en Wang, Puqing

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Song, Jinhui

× Song, Jinhui

en Song, Jinhui

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Kanda, Hideyuki

× Kanda, Hideyuki

en Kanda, Hideyuki

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Hayakawa, Takehito

× Hayakawa, Takehito

en Hayakawa, Takehito

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Kumagai, Tomohiro

× Kumagai, Tomohiro

en Kumagai, Tomohiro

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Kakamu, Takeyasu

× Kakamu, Takeyasu

en Kakamu, Takeyasu

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Tsuji, Masayoshi

× Tsuji, Masayoshi

en Tsuji, Masayoshi

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Hidaka, Tomoo

× Hidaka, Tomoo

en Hidaka, Tomoo

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Mori, Yayoi

× Mori, Yayoi

en Mori, Yayoi

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権利情報
権利情報 © 2014 The Fukushima Society of Medical Science
内容記述
内容記述タイプ Abstract
内容記述 Objectives: From our previous results, manganese (Mn) and iron (Fe) in the blood of Parkinson's disease (PD) patients without depression were higher than those of both the PD patients with depression and controls, the hypothesis that "two types of PD exist-PD without depression and affected by Mn and Fe, and PD with depression and unaffected by Mn or Fe" was induced. To investigate the hypothesis, correlations among blood and urine metals were compared in the subjects. Methods: Subjects comprised PD patients with depression, PD patients without depression and controls recruited from an outpatient clinic in China. Morning blood and urine samples were used to measure concentrations of metals. Results: In the controls, Mn, Fe and zinc (Zn) levels in blood strongly correlated with each other. The correlation coefficient between Mn and Zn in blood was significant in the PD patients with depression and the controls, but not in the PD patients without depression. Correlations of Fe between blood and urine in the PD patients without depression were significant, but not in the PD patients with depression and the controls. Conclusions: A common route of simultaneous intake of Mn, Fe and Zn could exist in our subjects, however in PD patients without depression, a large intake of Mn may have been from another route. Some results of the PD patients without depression were different from those of the PD patients with depression and the controls. Thus, two types of PD may exist.
出版者
出版者 The Fukushima Society of Medical Science
言語
言語 eng
書誌情報 en : Fukushima Journal of Medical Science

巻 60, 号 2, p. 108-115, 発行日 2014
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.5387/fms.2014-8
関連情報
識別子タイプ PMID
関連識別子 25283978
関連情報
識別子タイプ ICHUSHI
関連識別子 2016153987
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0016-2590
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2185-4610
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA0065246X
主題
主題Scheme Other
主題 Parkinson's disease
主題
主題Scheme Other
主題 Depression
主題
主題Scheme Other
主題 Heavy metals
主題
主題Scheme Other
主題 Correlation
主題
主題Scheme Other
主題 Blood and urine levels
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