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Therapeutic efficacy of pregabalin in patients with leg symptoms due to lumbar spinal stenosis
https://fmu.repo.nii.ac.jp/records/2001854
https://fmu.repo.nii.ac.jp/records/2001854fae28b45-f9ef-48c2-a885-6cacd10aa38e
| 名前 / ファイル | ライセンス | アクション |
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FksmJMedSci_60_p35.pdf (221.4 KB)
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| Item type | デフォルトアイテムタイプ（フル）fmu(1) | |||||||||||||||||||
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| 公開日 | 2014-09-19 | |||||||||||||||||||
| タイトル | ||||||||||||||||||||
| タイトル | Therapeutic efficacy of pregabalin in patients with leg symptoms due to lumbar spinal stenosis | |||||||||||||||||||
| 言語 | en | |||||||||||||||||||
| 作成者 |
Takahashi, Naoto
× Takahashi, Naoto
× Arai, Itaru
× Kayama, Satoru
× Ichiji, Kenji
× Fukuda, Hironari
× Kaga, Takahiro
× Konno, Shin-Ichi
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| 権利情報 | ||||||||||||||||||||
| 権利情報 | © 2014 The Fukushima Society of Medical Science | |||||||||||||||||||
| 内容記述 | ||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||
| 内容記述 | The purpose of this study was to evaluate the therapeutic efficacy of pregabalin in patients with leg symptoms due to lumbar spinal stenosis. Study subjects were classified into two groups according to their pharmacotherapy: the pregabalin group, treated with nonsteroidal anti-inflammatory drug and pregabalin combination therapy, and the control group, treated with nonsteroidal anti-inflammatory drug monotherapy. The two groups were compared in terms of the duration of pain after the onset of leg symptoms and the type of neurogenic intermittent claudication, whether radicular-, caudal-, or mixed-type. Numerical rating scale and Roland-Morris Disability Questionnaire scores were evaluated before and 3 months after treatment. After 3 months of treatment, there were significant differences in the numerical rating scale for radicular- and mixed-types, but not for caudal-type, between the two groups in the subjects with leg symptoms for greater than 3 months. There were significant differences between the two groups in Roland-Morris Disability Questionnaire scores for mixed-type, but not for radicular- and caudal-types, in the subjects with leg symptoms for less than 3 months and for radicular- and mixed-types, but not for caudal-type, in the subjects with leg symptoms for greater than 3 months. Nonsteroidal anti-inflammatory drug and pregabalin combination therapy may be more effective than nonsteroidal anti-inflammatory drug monotherapy for the relief of leg symptoms due to lumbar spinal stenosis, preventing aggravation of subjective symptoms and improving quality of life for patients with radicular- and mixed-types in subjects with leg symptoms for greater than 3 months, although it may be necessary to consider alternative therapy for patients with caudal-type. | |||||||||||||||||||
| 出版者 | ||||||||||||||||||||
| 出版者 | The Fukushima Society of Medical Science | |||||||||||||||||||
| 言語 | ||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||
| 書誌情報 |
en : Fukushima Journal of Medical Science 巻 60, 号 1, p. 35-42, 発行日 2014-08-08 |
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| 関連タイプ | isIdenticalTo | |||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||
| 関連識別子 | https://doi.org/10.5387/fms.2013-22 | |||||||||||||||||||
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| 識別子タイプ | PMID | |||||||||||||||||||
| 関連識別子 | 25030722 | |||||||||||||||||||
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| 識別子タイプ | ICHUSHI | |||||||||||||||||||
| 関連識別子 | 2015176970 | |||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||
| 収録物識別子 | ||||||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||||||
| 収録物識別子 | 0016-2590 | |||||||||||||||||||
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| 収録物識別子タイプ | EISSN | |||||||||||||||||||
| 収録物識別子 | 2185-4610 | |||||||||||||||||||
| 収録物識別子 | ||||||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||||||
| 収録物識別子 | AA0065246X | |||||||||||||||||||
| 主題 | ||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||
| 主題 | Lumbar spinal stenosis | |||||||||||||||||||
| 主題 | ||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||
| 主題 | Neurogenic intermittent claudication | |||||||||||||||||||
| 主題 | ||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||
| 主題 | Pregabalin | |||||||||||||||||||
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| 主題Scheme | Other | |||||||||||||||||||
| 主題 | Neuropathic pain | |||||||||||||||||||
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| 主題Scheme | Other | |||||||||||||||||||
| 主題 | Therapeutic efficacy | |||||||||||||||||||
