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  1. 福島医学会
  2. Fukushima Journal of Medical Science
  3. Vol.58 (2012)

A reduction of coronary flow reserve is associated with chronic kidney disease and long-term cardio-cerebrovascular events in patients with non-obstructive coronary artery disease and vasospasm

https://fmu.repo.nii.ac.jp/records/2001828
https://fmu.repo.nii.ac.jp/records/2001828
5e515b5e-beef-47d9-af10-7106b639f34c
名前 / ファイル ライセンス アクション
FksmJMedSci_58_p136.pdf FksmJMedSci_58_p136.pdf (339.2 KB)
Item type デフォルトアイテムタイプ(フル)fmu(1)
公開日 2012-12-25
タイトル
タイトル A reduction of coronary flow reserve is associated with chronic kidney disease and long-term cardio-cerebrovascular events in patients with non-obstructive coronary artery disease and vasospasm
言語 en
作成者 Sakamoto, Nobuo

× Sakamoto, Nobuo

en Sakamoto, Nobuo

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Iwaya, Shoji

× Iwaya, Shoji

en Iwaya, Shoji

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Owada, Takashi

× Owada, Takashi

en Owada, Takashi

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Nakamura, Yuichi

× Nakamura, Yuichi

en Nakamura, Yuichi

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Yamauchi, Hiroyuki

× Yamauchi, Hiroyuki

en Yamauchi, Hiroyuki

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Hoshino, Yasuto

× Hoshino, Yasuto

en Hoshino, Yasuto

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Mizukami, Hiroyuki

× Mizukami, Hiroyuki

en Mizukami, Hiroyuki

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Sugimoto, Koichi

× Sugimoto, Koichi

en Sugimoto, Koichi

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Yamaki, Takayoshi

× Yamaki, Takayoshi

en Yamaki, Takayoshi

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Kunii, Hiroyuki

× Kunii, Hiroyuki

en Kunii, Hiroyuki

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Nakazato, Kazuhiko

× Nakazato, Kazuhiko

en Nakazato, Kazuhiko

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Suzuki, Hitoshi

× Suzuki, Hitoshi

en Suzuki, Hitoshi

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Saitoh, Shu-Ichi

× Saitoh, Shu-Ichi

en Saitoh, Shu-Ichi

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Takeishi, Yasuchika

× Takeishi, Yasuchika

en Takeishi, Yasuchika

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権利情報
権利情報 © 2012 The Fukushima Society of Medical Science
内容記述
内容記述タイプ Abstract
内容記述 Background: Coronary flow reserve (CFR) provides essential information about the coronary microvasculature. Chronic kidney disease (CKD) is a risk factor for cardio-cerebrovascular diseases. We hypothesized that low CFR is associated with CKD and long-term cardio-cerebrovascular events in the patients without obstructive coronary artery diseases and vasospasm. Method and Results: In this study, 73 patients suspected with coronary artery disease but had no epicardial coronary stenosis and vasospasm were enrolled. There were 13 CKD patients and CFR was measured using the Doppler flow wire methods in the left anterior descending artery. CFR was significantly lower in CKD group than non-CKD group (3.13±0.6 vs. 4.00±1.1, P=0.007). From multivariate logistic regression analysis, the independent factor associated with the presence of CKD was only CFR (odds ratio 3.85, 95% confidence interval 1.27-11.70, P=0.017). In the patients with low CFR (≤ 2.8), cardio-cerebrovascular events were more common than those with normal CFR (CFR > 2.8). Besides, in the patients who had both low CFR and CKD, long-term cardio-cerebrovascular events were more likely to occur than those with normal CFR or non-CKD. Conclusions: Our data suggest that low CFR is associated with CKD and cardio-cerebrovascular events in the patients without coronary stenosis and vasospasm.
出版者
出版者 The Fukushima Society of Medical Science
言語
言語 eng
書誌情報 en : Fukushima Journal of Medical Science

巻 58, 号 2, p. 136-143, 発行日 2012
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.5387/fms.58.136
関連情報
識別子タイプ PMID
関連識別子 23237869
関連情報
識別子タイプ ICHUSHI
関連識別子 2013249054
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 0016-2590
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 2185-4610
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA0065246X
主題
主題Scheme Other
主題 coronary flow reserve (CFR)
主題
主題Scheme Other
主題 doppler flow wire
主題
主題Scheme Other
主題 coronary microcirculation
主題
主題Scheme Other
主題 chronic kidney disease (CKD)
主題
主題Scheme Other
主題 cardio-cerebrovascular event
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