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A challenge to appropriate antibiotic use in children with respiratory infections: a 5-year single-institution experience
https://fmu.repo.nii.ac.jp/records/2001797
https://fmu.repo.nii.ac.jp/records/2001797899d0173-d575-46bd-b7fb-b0f67112b29c
| 名前 / ファイル | ライセンス | アクション |
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FksmJMedSci_57_p33.pdf (390.3 KB)
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| Item type | デフォルトアイテムタイプ（フル）fmu(1) | |||||||||||||
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| 公開日 | 2012-05-24 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | A challenge to appropriate antibiotic use in children with respiratory infections: a 5-year single-institution experience | |||||||||||||
| 言語 | en | |||||||||||||
| 作成者 |
Matsumoto, Ayumi
× Matsumoto, Ayumi
× Hashimoto, Koichi
× Kawasaki, Yukihiko
× Hosoya, Mitsuaki
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| 権利情報 | ||||||||||||||
| 権利情報 | © 2011 The Fukushima Society of Medical Science | |||||||||||||
| 内容記述 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | BACKGROUND: We have studied the rate of emergence of antibiotic-resistant Streptococcus pneumoniae (S. pneumoniae) and Haemophilus influenzae (H. influenzae) and the subsequent antibiotic use in host patients of those isolates at the Department of Pediatrics, Soma General Hospital, Fukushima. Moreover, we carried out several studies investigating the risks and benefits of antibiotic-free treatment for children with respiratory infections. In this report, we summarize our research and suggest better treatment options for pediatric patients with respiratory infections. METHODS: We investigated the necessity of antibiotic use in the treatment of pediatric inpatients with respiratory syncytial virus (RSV) infection, and tested our hypothesis that antibiotic-free treatment for common cold will reduce the number of resistant S. pneumoniae strains in the pediatric nasopharynx. Therefore, we restricted prescribing antibiotics for pediatric patients with respiratory infections. The rates of resistant S. pneumoniae and H. influenzae and the medication history of the host patients before and after the intervention were compared. RESULTS: We found that most of the RSV-infected patients recovered without antibiotic treatment, and that the antibiotic-free treatment inhibited the emergence of antibiotic-resistant strains. The rate of penicillin-resistant S. pneumoniae decreased but the rate of ampicillin-resistant H. influenzae did not change significantly during the study. CONCLUSION: We concluded that patients with respiratory infections can be treated without antibiotics, under careful examination and observation. Continued monitoring of such new interventions as well as recommending their use to other caregivers and physicians will help inhibit the spread of resistant strains. | |||||||||||||
| 出版者 | ||||||||||||||
| 出版者 | The Fukushima Society of Medical Science | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 書誌情報 |
en : Fukushima Journal of Medical Science 巻 57, 号 2, p. 33-45, 発行日 2011 |
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| 関連タイプ | isIdenticalTo | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.5387/fms.57.33 | |||||||||||||
| 関連情報 | ||||||||||||||
| 識別子タイプ | PMID | |||||||||||||
| 関連識別子 | 22353649 | |||||||||||||
| 関連情報 | ||||||||||||||
| 識別子タイプ | ICHUSHI | |||||||||||||
| 関連識別子 | 2013106772 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
| 収録物識別子 | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 0016-2590 | |||||||||||||
| 収録物識別子 | ||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||
| 収録物識別子 | 2185-4610 | |||||||||||||
| 収録物識別子 | ||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA0065246X | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Streptococcus pneumoniae | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | antibiotics | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | common cold | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | children | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | MeSH | |||||||||||||
| 主題 | Anti-Bacterial Agents | |||||||||||||
| 主題 | ||||||||||||||
| 主題Scheme | MeSH | |||||||||||||
| 主題 | Child | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Common Cold | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Drug Resistance, Microbial | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Haemophilus Infections | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Haemophilus influenzae | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Humans | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Inappropriate Prescribing | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Pneumococcal Infections | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Respiratory Syncytial Virus Infections | |||||||||||||
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| 主題Scheme | MeSH | |||||||||||||
| 主題 | Respiratory Tract Infections | |||||||||||||
