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The role of FB21 as a marker of glomerular endothelial cell injury
https://fmu.repo.nii.ac.jp/records/2001719
https://fmu.repo.nii.ac.jp/records/2001719107b87e6-ce39-49f5-bb49-9773b6692e5f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
FksmJMedSci_52_p35.pdf (1.6 MB)
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| Item type | デフォルトアイテムタイプ（フル）fmu(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2011-05-26 | |||||||
| タイトル | ||||||||
| タイトル | The role of FB21 as a marker of glomerular endothelial cell injury | |||||||
| 言語 | en | |||||||
| 作成者 |
Kawasaki, Yukihiko
× Kawasaki, Yukihiko
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| 権利情報 | ||||||||
| 権利情報 | © 2006 The Fukushima Society of Medical Science | |||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | FB21 was reactive with the glomerular endothelial cells and distal tubules of the human kidney and was bound to a sialic-acid-dependent cell surface antigen. We evaluated the FB21 staining in fetal kidneys, and the kidneys of children and adults with normal kidneys and glomerulonephritis and investigated whether FB21 can be used as a marker for endothelial cell injury. FB21 was reactive with the endothelial cells of normal kidneys and was detected on the surface of endothelial cells by immunoelectron microscopy. FB21 was reactive with endothelial cells in the kidneys of over 32-week fetuses. The endothelial cell FB21 staining scores in the first renal biopsy specimens of patients with hemolytic uremic syndrome (HUS) were lower than in the kidneys of children with normal kidneys and was negatively correlated with their serum E-selectin concentrations. The FB21 staining of glomerular endothelial cells was similar to the staining for the other endothelial markers, CD34 and von Willebrand factor (vWF). However, FB21 staining of interstitial blood vessels was very weak and was distinct from that of other endothelial markers. These results suggest that FB21 can be used as a specific marker for glomerular endothelial cell injury in various types of glomerulonephritis. | |||||||
| 出版者 | ||||||||
| 出版者 | The Fukushima Society of Medical Science | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 書誌情報 |
en : Fukushima Journal of Medical Science 巻 52, 号 2, p. 35-43, 発行日 2006-12 |
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| 関連情報 | ||||||||
| 関連タイプ | isIdenticalTo | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.5387/fms.52.35 | |||||||
| 関連情報 | ||||||||
| 識別子タイプ | PMID | |||||||
| 関連識別子 | 17427754 | |||||||
| 関連情報 | ||||||||
| 識別子タイプ | ICHUSHI | |||||||
| 関連識別子 | 2007203245 | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 出版タイプ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 0016-2590 | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | EISSN | |||||||
| 収録物識別子 | 2185-4610 | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA0065246X | |||||||
| 主題 | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | Glomerular endothelium | |||||||
| 主題 | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | markers of endothelial cell | |||||||
| 主題 | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | FB21 | |||||||
| 主題 | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | E-selectin | |||||||
| 主題 | ||||||||
| 主題Scheme | MeSH | |||||||
| 主題 | Animals | |||||||
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| 主題Scheme | MeSH | |||||||
| 主題 | Antibodies, Monoclonal | |||||||
| 主題 | ||||||||
| 主題Scheme | MeSH | |||||||
| 主題 | Antigens, Surface | |||||||
| 主題 | ||||||||
| 主題Scheme | MeSH | |||||||
| 主題 | Biological Markers | |||||||
| 主題 | ||||||||
| 主題Scheme | MeSH | |||||||
| 主題 | Endothelial Cells | |||||||
| 主題 | ||||||||
| 主題Scheme | MeSH | |||||||
| 主題 | Glomerulonephritis | |||||||
| 主題 | ||||||||
| 主題Scheme | MeSH | |||||||
| 主題 | Hemolytic-Uremic Syndrome | |||||||
| 主題 | ||||||||
| 主題Scheme | MeSH | |||||||
| 主題 | Humans | |||||||
| 主題 | ||||||||
| 主題Scheme | MeSH | |||||||
| 主題 | Kidney Glomerulus | |||||||
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| 主題Scheme | MeSH | |||||||
| 主題 | N-Acetylneuraminic Acid | |||||||
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| 主題Scheme | MeSH | |||||||
| 主題 | Staining and Labeling | |||||||
