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  1. 医学部
  2. 学術雑誌論文

Polytetrafluoroethylene fume-induced pulmonary edema: a case report and review of the literature

https://fmu.repo.nii.ac.jp/records/2000029
https://fmu.repo.nii.ac.jp/records/2000029
7565e6b4-9a50-498c-a13e-3f294d2a861f
名前 / ファイル ライセンス アクション
s13256-015-0593-9.pdf s13256-015-0593-9.pdf (656.8 KB)
Item type デフォルトアイテムタイプ(フル)fmu(1)
公開日 2015-08-06
タイトル
タイトル Polytetrafluoroethylene fume-induced pulmonary edema: a case report and review of the literature
言語 en
作成者 Hamaya, Rikuta

× Hamaya, Rikuta

en Hamaya, Rikuta

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Ono, Yuko

× Ono, Yuko

en Ono, Yuko

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Chida, Yasuyuki

× Chida, Yasuyuki

en Chida, Yasuyuki

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Inokuchi, Ryota

× Inokuchi, Ryota

en Inokuchi, Ryota

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Kikuchi, Ken

× Kikuchi, Ken

en Kikuchi, Ken

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Tameda, Tadanobu

× Tameda, Tadanobu

en Tameda, Tadanobu

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Tase, Choichiro

× Tase, Choichiro

en Tase, Choichiro

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権利情報
権利情報Resource http://creativecommons.org/licenses/by/4.0
権利情報 © 2015 Hamaya et al.; licensee BioMed Central.
内容記述
内容記述タイプ Abstract
内容記述 INTRODUCTION: Polytetrafluoroethylene is ubiquitous in materials commonly used in cooking and industrial applications. Overheated polytetrafluoroethylene can generate toxic fumes, inducing acute pulmonary edema in some cases. However, neither the etiology nor the radiological features of this condition have been determined. For clarification, we report an illustrative case, together with the first comprehensive literature review. CASE PRESENTATION: A previously healthy 35-year-old Japanese man who developed severe dyspnea presented to our hospital. He had left a polytetrafluoroethylene-coated pan on a gas-burning stove for 10 hours while unconscious. Upon admission, he was in severe respiratory distress. A chest computed tomographic scan showed massive bilateral patchy consolidations with ground-glass opacities and peripheral area sparing. A diagnosis of polytetrafluoroethylene fume-induced pulmonary edema was made. He was treated with non-invasive positive pressure ventilation and a neutrophil elastase inhibitor, which dramatically alleviated his symptoms and improved his oxygenation. He was discharged without sequelae on hospital day 11. A literature review was performed to survey all reported cases of polytetrafluoroethylene fume-induced pulmonary edema. We searched the PubMed, Embase, Web of Science and OvidSP databases for reports posted between the inception of the databases and 30 September 2014, as well as several Japanese databases (Ichushi Web, J-STAGE, Medical Online, and CiNii). Two radiologists independently interpreted all chest computed tomographic images. Eighteen relevant cases (including the presently reported case) were found. Our search revealed that (1) systemic inflammatory response syndrome was frequently accompanied by pulmonary edema, and (2) common computed tomography findings were bilateral ground-glass opacities, patchy consolidation and peripheral area sparing. Pathophysiological and radiological features were consistent with the exudative phase of acute respiratory distress syndrome. However, the contrast between the lesion and the spared peripheral area was striking and was distinguishable from the common radiological features of acute respiratory distress syndrome. CONCLUSION: The essential etiology of polytetrafluoroethylene fume-induced pulmonary edema seems to be increased pulmonary vascular permeability caused by an inflammatory response to the toxic fumes. The radiological findings that distinguish polytetrafluoroethylene fume-induced pulmonary edema can be bilateral ground-glass opacity or a patchy consolidation with clear sparing of the peripheral area.
出版者
出版者 BioMed Central
言語
言語 eng
書誌情報 en : Journal of medical case reports

巻 9, p. 111, 発行日 2015-05-14
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.1186/s13256-015-0593-9
関連情報
識別子タイプ PMID
関連識別子 25971706
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 1752-1947
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