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Delayed and acute hemolytic transfusion reactions due to red cell antibodies and red cell-reactive HLA antibodies
https://fmu.repo.nii.ac.jp/records/2000004
https://fmu.repo.nii.ac.jp/records/20000043c580827-013b-49c3-8518-6a14fe359be7
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Transfusion_45_1925.pdf (709.9 KB)
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| Item type | デフォルトアイテムタイプ（フル）fmu(1) | |||||||||||||||||
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| 公開日 | 2010-05-24 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | Delayed and acute hemolytic transfusion reactions due to red cell antibodies and red cell-reactive HLA antibodies | |||||||||||||||||
| 言語 | en | |||||||||||||||||
| 作成者 |
Takeuchi, Chikako
× Takeuchi, Chikako
× Ohto, Hitoshi
× Miura, Saori
× Yasuda, Hiroyasu
× Ono, Satoshi
× Ogata, Takashi
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| 権利情報 | ||||||||||||||||||
| 権利情報 | © 2005 American Association of Blood Banks. The definitive version is available at www.blackwell-synergy.com. | |||||||||||||||||
| 内容記述 | ||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||
| 内容記述 | Background：It has been controversial whether HLA antibodies cause hemolytic transfusion reactions (HTR) or shortened RBC survival. We report a patient who had two episodes of HTR, the latter of which was likely due to RBC-reactive HLA antibodies. Case Report：A 77-year-old woman, admitted for gastric varix rupture, had no RBC irregular antibodies detected before transfusion. On hospital day 12, after transfusion of two units of RBCs and two units of FFP, the first delayed hemolytic episode occurred and anti-E, anti-c, anti-Jka and unidentified RBC-reactive antibodies were detected in serum from day 14. Two further units of compatible RBCs were transfused using a leukocyte-reduction filter on days 19 and 22. After 4 hours of starting a transfusion on day 22, the patient had fever, and a second hemolytic episode was recorded. Multireactive HLA antibodies (reactive against 20 of 20 donor panel lymphocytes) were detected in sera from day 15 to day 21. These HLA antibodies reacted strongly with HLA-A2 and HLA-B7 antigens, corresponding to Bgc and Bga antigens on RBCs, respectively. RBCs transfused on day 22 were found to be HLA-A2 by genotyping.\nConclusion： Strong HLA alloantibodies in this recipient appear to have caused a HTR. It is suggested that HLA antibodies be considered in patients with unexplained HTRs. | |||||||||||||||||
| 出版者 | ||||||||||||||||||
| 出版者 | Blackwell Publishing Inc. | |||||||||||||||||
| 言語 | ||||||||||||||||||
| 言語 | eng | |||||||||||||||||
| 書誌情報 |
en : Transfusion 巻 45, 号 12, p. 1925-1929, 発行日 2005-12 |
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| 関連情報 | ||||||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||
| 関連識別子 | https://doi.org/10.1111/j.1537-2995.2005.00607.x | |||||||||||||||||
| 関連情報 | ||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||
| 関連識別子 | 16371045 | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||
| 出版タイプ | ||||||||||||||||||
| 出版タイプ | AM | |||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||||
| 収録物識別子 | ||||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||||
| 収録物識別子 | 0041-1132 | |||||||||||||||||
| 収録物識別子 | ||||||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||||||
| 収録物識別子 | 1537-2995 | |||||||||||||||||
| 収録物識別子 | ||||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||||
| 収録物識別子 | AA00868753 | |||||||||||||||||
| 主題 | ||||||||||||||||||
| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Acute Disease | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Aged | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Blood Transfusion | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Erythrocytes | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Female | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | HLA-A2 Antigen | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | HLA-B7 Antigen | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Hemolysis | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Histocompatibility Testing | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Humans | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Isoantibodies | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Liver Cirrhosis | |||||||||||||||||
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| 主題Scheme | MeSH | |||||||||||||||||
| 主題 | Time Factors | |||||||||||||||||
