| Item type |
デフォルトアイテムタイプ(フル)fmu(1) |
| 公開日 |
2025-10-03 |
| タイトル |
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|
タイトル |
Prognosis of pregnant women with epilepsy and their neonates: a case series study |
|
言語 |
en |
| 作成者 |
Masamoto, Hitoshi
Murata, Momoko
Ooshiro, Miya
Inamine, Morihiko
Uesato, Tadakazu
Nagasaki, Hiraku
Hiyane, Masato
Nakamoto, Masaya
Hironaka, Kouhei
|
| 権利情報 |
|
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
|
権利情報 |
© 2025 The Fukushima Society of Medical Science. This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license. |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
OBJECTIVES: To explore the outcomes of pregnant women with epilepsy and their neonates, including the incidence of neonatal withdrawal syndrome. METHODS: In total, 26 pregnancies in 20 mothers with epilepsy were retrospectively examined for the presence of complications before and during pregnancy, number of antiseizure medications taken, gestational weeks at delivery, mode of delivery, number of seizure episodes during pregnancy and postpartum, neonatal birth weight, Apgar score, pH of the umbilical cord arterial blood, neonatal abnormalities, and neonatal withdrawal syndrome. RESULTS: Overall, 25 of the 26 pregnancies resulted in live births, with 4 cases undergoing premature deliveries. Ten cases underwent cesarean section, with only one case undergoing cesarean section due to the fear of experiencing seizure during vaginal delivery. During pregnancy, two cases experienced one seizure episode. The rate of small for gestational age was 8.0%, and three neonates had congenital abnormalities. Withdrawal symptoms were observed in 75% of the neonates, but none of them obtained ≥8 points in the withdrawal checklist, the threshold for pharmacotherapy. CONCLUSIONS: For women with epilepsy who receive medical management and establish good control prior to pregnancy, child birth may be relatively safe, with a low rate of neonatal withdrawal syndrome requiring pharmacotherapy. |
| 出版者 |
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|
出版者 |
The Fukushima Society of Medical Science |
| 言語 |
|
|
言語 |
eng |
| 書誌情報 |
en : Fukushima journal of medical science
巻 71,
号 4,
p. 235-241,
発行日 2025
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| 関連情報 |
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関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.5387/fms.24-00048 |
| 関連情報 |
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|
識別子タイプ |
PMID |
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関連識別子 |
40268411 |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
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|
収録物識別子タイプ |
PISSN |
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収録物識別子 |
0016-2590 |
| 収録物識別子 |
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|
収録物識別子タイプ |
EISSN |
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収録物識別子 |
2185-4610 |
| 収録物識別子 |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0065246X |
| 主題 |
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|
主題Scheme |
Other |
|
主題 |
epilepsy |
| 主題 |
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|
主題Scheme |
Other |
|
主題 |
pregnancy |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
maternal outcome |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
neonatal outcome |
| 主題 |
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|
主題Scheme |
Other |
|
主題 |
neonatal withdrawal syndrome |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Humans |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Female |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Pregnancy |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Epilepsy |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Infant, Newborn |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Retrospective Studies |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Adult |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Prognosis |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Pregnancy Complications |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Anticonvulsants |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Neonatal Abstinence Syndrome |
| 主題 |
|
|
主題Scheme |
MeSH |
|
主題 |
Pregnancy Outcome |