{"created":"2024-12-06T07:16:35.377363+00:00","id":2002141,"links":{},"metadata":{"_buckets":{"deposit":"b8ed1fc8-6a8f-47f2-bf96-0d4cd1ff7fe0"},"_deposit":{"created_by":8,"id":"2002141","owners":[8],"pid":{"revision_id":0,"type":"depid","value":"2002141"},"status":"published"},"_oai":{"id":"oai:fmu.repo.nii.ac.jp:02002141","sets":["1732778801467:1733287270801:1733467661287:1733467739556"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"初回手術から1年後に肺転移で再発した卵巣粘液性境界悪性腫瘍の1例","subitem_title_language":"ja"}]},"item_1617186385884":{"attribute_name":"Alternative Title","attribute_value_mlt":[{"subitem_alternative_title":"Mucinous borderline ovarian tumors recurred with lung metastasis 1 year after initial surgery: A case report","subitem_alternative_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorAlternatives":[{"creatorAlternative":"Watanabe, Takeshi","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"渡邉, 健史","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Kojima, Manabu","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"小島, 学","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Okabe, Chikako","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"岡部, 慈子","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Sato, Tetsu","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"佐藤, 哲","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Ueda, Makiko","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"植田, 牧子","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Kamo, Norihito","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"加茂, 矩士","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Endo, Yuta","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"遠藤, 雄大","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Furukawa, Sigenori","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"古川, 茂宜","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Soeda, Shu","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"添田, 周","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Watanabe, Takafumi","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"渡邉, 尚文","creatorNameLang":"ja"}]},{"creatorAlternatives":[{"creatorAlternative":"Fujimori, Keiya","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"藤森, 敬也","creatorNameLang":"ja"}]}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2022 福島医学会","subitem_rights_language":"ja"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"卵巣粘液性境界悪性腫瘍","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"TTF-1","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"転移性肺腫瘍","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Mucinous borderline ovarian tumor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Thyroid transcription factor-1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Metastatic lung tumor","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"卵巣粘液性境界悪性腫瘍（mucinous borderline ovarian tumor ; MBOT）は，再発することの少ない予後良好な疾患として知られている。まれに再発を経験することはあるが，腹腔内における再発がほとんどである。今回我々は，初回手術から1年後に肺転移で再発した，希少な経過を辿ったMBOTの症例を経験したので報告する。症例は60歳代の2経妊2経産の女性で，1ヶ月続く労作時呼吸苦を主訴に近医診療所を受診し，骨盤内腫瘍と胸水貯留を指摘され，さらなる精査のため福島県立医科大学附属病院産婦人科に紹介となった。画像検査で15cm大の多房性嚢胞性腫瘍が認められたことから卵巣がんが疑われ，腹式単純子宮全摘術，両側付属器切除術，大網部分切除術が行われた。組織診断はMBOTでpT1cN0M0，ステージICと診断した。術後補助化学療法は行わずに経過観察をしていたが，術後1年で撮影したCTで両下肺野に1箇所ずつ小結節影を認めた。胸腔鏡下両肺下葉切除術がおこなわれ，肺病変の組織像は卵巣腫瘍，すなわちMBOTとの形態学的類似性がみられていた。また，肺病変と卵巣腫瘍の免疫組織学的プロファイルが一致していたことや，原発性肺腺癌で高率に陽性となるTTF-1（Thyroid transcription factor-1）が陰性であったことから，MBOTの肺転移再発と診断した。MBOTの肺転移は非常にまれであるが，早期進行期での再発例や，初回手術後に長期間経過してからの再発例が報告されており，進行期の程度によらず肺も含めた長期間のサーベイランスが必要であることが示唆された。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"Mucinous borderline ovarian tumors (MBOT) are known to have a good prognosis with a low recurrence rate, and most recurrences occur in the abdominal cavity. We herein describe a case of MBOT which recurred with metastasis to the lung one year following initial surgery. A 60-year-old female gravida 2 para 2 presented to her local clinic complaining of exertional dyspnea lasting over one cytokeramonth. She was found to have a pelvic tumor and pleural effusions, and was referred to the department of obstetrics and gynecology of Fukushima Medical University Hospital for further examination. A multilocular cystic tumor measuring 15 cm in diameter was observed via imaging, leading to a suspicion of ovarian cancer, and abdominal, simple hysterectomy, bilateral adnexectomy, and partial omentectomy were performed. The tumor was histologically diagnosed as pT1cN0M0 stage IC MBOT. The patient was followed up without any adjuvant chemotherapy ; however, a CT taken 1 year following surgery revealed nodular shadows, with one each in both lower lung fields. A thoracoscopic bilateral lung lobectomy was conducted, and the resected lung lesion indicated morphological similarities to the ovarian tumor (MBOT). Furthermore, because the immunohistological profile of the lung lesion and the ovarian tumor matched, and thyroid transcription factor-1(TTF-1), which is usually positive in primary pulmonary adenocarcinomas, was negative. Based on these findings, we diagnosed the lung lesion as a metastatic recurrence of MBOT. Although lung metastatic recurrence of MBOT is very rare, there are reports on recurrence in the early stages or after a long interval following initial surgery, thus suggesting a need for long-term surveillance of tumor recurrence including the lungs metastasis, regardless of the disease stage.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"福島医学会","subitem_publisher_language":"ja"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0016-2582","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2436-7826","subitem_source_identifier_type":"EISSN"},{"subitem_source_identifier":"AN00216776","subitem_source_identifier_type":"NCID"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"42","bibliographicPageStart":"37","bibliographicVolumeNumber":"72","bibliographic_titles":[{"bibliographic_title":"福島医学雑誌","bibliographic_titleLang":"ja"}]}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.5387/fmedj.72.1_37","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"2022204115","subitem_relation_type_select":"ICHUSHI"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-06-03"}],"displaytype":"detail","filename":"FksmMedJ_72_p37.pdf","filesize":[{"value":"2.0 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://fmu.repo.nii.ac.jp/record/2002141/files/FksmMedJ_72_p37.pdf"},"version_id":"440c1086-b889-492c-a4e3-3f201903fdcf"}]},"item_title":"初回手術から1年後に肺転移で再発した卵巣粘液性境界悪性腫瘍の1例","item_type_id":"40002","owner":"8","path":["1733467739556"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-06-03"},"publish_date":"2022-06-03","publish_status":"0","recid":"2002141","relation_version_is_last":true,"title":["初回手術から1年後に肺転移で再発した卵巣粘液性境界悪性腫瘍の1例"],"weko_creator_id":"8","weko_shared_id":-1},"updated":"2024-12-27T09:00:59.262442+00:00"}