{"created":"2024-12-02T02:07:09.816798+00:00","id":2001894,"links":{},"metadata":{"_buckets":{"deposit":"32a64a78-486f-4dd5-a361-336d98509ced"},"_deposit":{"created_by":8,"id":"2001894","owners":[8],"pid":{"revision_id":0,"type":"depid","value":"2001894"},"status":"published"},"_oai":{"id":"oai:fmu.repo.nii.ac.jp:02001894","sets":["1732778801467:1732778962699:1733104663995"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Brain hypothermia therapy for neonatal hypoxic-ischemic encephalopathy with a severely elevated serum creatine kinase level","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kinoshita, Hidetoshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Imamura, Takashi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Maeda, Hajime","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shibukawa, Yasuko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Fukuda, Yutaka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kin, Shogo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ariga, Hiromichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nagasawa, Katsutoshi","creatorNameLang":"en"}]}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2015 The Fukushima Society of Medical Science","subitem_rights_language":"en"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"creatine kinase","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hypothermia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hypoxic-ischemic encephalopathy","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Several studies have shown that brain hypothermia therapy (BHT) after neonatal hypoxic-ischemic encephalopathy (HIE) can improve neurodevelopmental outcomes. However, there have been no reports of the neurodevelopmental outcomes for the infant with a serum creatine kinase (CK) level above 20,000 IU/L in association with neonatal HIE. We report a female infant with a very high serum CK level (26,428 IU/L) associated with neonatal asphyxia. We diagnosed this infant with moderate HIE, and BHT was achieved by head cooling within 6 hours after birth to an esophageal temperature of 34.5°C. There were no significant adverse events during BHT, and the CK level spontaneously decreased. Although we report only the short-term outcomes for this case, she presents neurodevelopmental delays at the age of 18 months. It may be correlated between high serum CK level and long-term neurodevelopmental delays. Abbreviations: CK, creatine kinase; HIE, hypoxic-ischemic encephalopathy; BHT, brain hypothermia therapy; NRFS, non-reassuring fetal status; CK-MB, creatine kinase-myocardial band; MRI, magnetic resonance imaging; CK-BB, creatine kinase-brain band.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"The Fukushima Society of Medical Science","subitem_publisher_language":"en"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0016-2590","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2185-4610","subitem_source_identifier_type":"EISSN"},{"subitem_source_identifier":"AA0065246X","subitem_source_identifier_type":"NCID"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"57","bibliographicPageStart":"54","bibliographicVolumeNumber":"61","bibliographic_titles":[{"bibliographic_title":"Fukushima Journal of Medical Science","bibliographic_titleLang":"en"}]}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.5387/fms.2014-30","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"25946908","subitem_relation_type_select":"PMID"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"2016216420","subitem_relation_type_select":"ICHUSHI"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2015-08-05"}],"displaytype":"detail","filename":"FksmJMedSci_61_p54.pdf","filesize":[{"value":"554.5 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://fmu.repo.nii.ac.jp/record/2001894/files/FksmJMedSci_61_p54.pdf"},"version_id":"df8462d9-889f-4323-9b75-d5e46061e1ce"}]},"item_title":"Brain hypothermia therapy for neonatal hypoxic-ischemic encephalopathy with a severely elevated serum creatine kinase level","item_type_id":"40002","owner":"8","path":["1733104663995"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-08-05"},"publish_date":"2015-08-05","publish_status":"0","recid":"2001894","relation_version_is_last":true,"title":["Brain hypothermia therapy for neonatal hypoxic-ischemic encephalopathy with a severely elevated serum creatine kinase level"],"weko_creator_id":"8","weko_shared_id":-1},"updated":"2024-12-02T02:11:10.687276+00:00"}