2026-03-06T01:54:49Z https://fmu.repo.nii.ac.jp/oai

oai:fmu.repo.nii.ac.jp:02000017 2025-01-07T06:27:04Z 1623632832836:1730783669761

Measurement of Optic Nerve Blood Flow During Dissection of Parasellar Tumors Aimi, Yuri Saito, Kiyoshi Nagatani, Tetsuya Ito, Eiji Watanabe, Tadashi Wakabayashi, Toshihiko © Springer-Verlag 2008. The original Publication is available at www.springerlink.com. parasellar tumor optic nerve blood flow laser Doppler optic canal unroofing Adolescent Adult Aged Child Child, Preschool Dissection Female Humans Intraoperative Period Ischemia Laser-Doppler Flowmetry Male Middle Aged Neurosurgical Procedures Optic Nerve Pituitary Neoplasms Regional Blood Flow Sella Turcica Young Adult The authors describe direct measurement of optic nerve blood flow and examine application of such monitoring to detect optic nerve ischemia during parasellar tumor surgery. Twenty-six patients requiring surgery for parasellar tumors were evaluated prospectively. Ophthalmologic examination was performed before and after surgery. The optic nerve blood flow was measured using a laser Doppler flowmeter before tumor dissection (initial ONBF) and after tumor removal (final ONBF). The waveform was analyzed by a data acquisition system. In 16 patients, initial ONBF could be measured (22 nerves; 8.9±0.9 ml/100 g/min). Final ONBF could be determined in all 26 patients (42 nerves; 10.8±0.7 ml/100 g/min). In the 22 nerves with initial measurements, final ONBF (11.3±0.6 ml/100 g/min) was significantly increased (p<0.01). In 6 patients whose optic canal was unroofed, the optic nerve blood flow did not change immediately; nonetheless, an increase was prominent in the final phase (p<0.05). In another 6 patients, a small vessel adjacent to the optic nerve was temporarily occluded. The optic nerve blood flow was reduced demonstrably in 3 and recovered quickly after reperfusion. Intraoperative optic nerve blood flow measurement may be useful as a real-time monitoring for prediction and prevention of intraoperative optic nerve ischemia. Springer 2009-04 eng journal article AM https://fmu.repo.nii.ac.jp/records/2000017 https://doi.org/10.1007/s10143-008-0176-y 18853205 0344-5607 1437-2320 AA00324143 Neurosurgical review 32 2 199 205 https://fmu.repo.nii.ac.jp/record/2000017/files/NeurosurgRev_32_p199.pdf application/pdf 1.6 MB